Ollie Watkins scored a second-half winner for Brentford at Deepdale.
Nico Yennaris, who later went off with a head injury, nodded the Bees ahead after Florian Jozefzoon’s shot had been saved.
After Sean Maguire equalised, Romaine Sawyers’ strike restored Brentford’s lead.
Preston hit back again, this time courtesy of Tom Barkhuizen’s effort from the edge of the penalty area.
But Watkins secured the three points when he fired home after being found by Jozefzoon’s low cross.
This post was last modified on 28/10/2017