Brentford 1 Tranmere 2
Brentford lost their unbeaten home record, suffering a first league defeat since October.
Leaders Tranmere were in front at half-time courtesy of an Andy Robinson penalty after Harlee Dean had brought down David Amoo in the box.
Dean redeemed himself by levelling just after the break, heading home a Jake Bidwell free-kick.
But Adam McGurk notched the winner after an hour, nutmegging Bidwell and beating keeper Simon Moore from an acute angle.
A heated tussle ensued after Harry Forrester appeared to kick out at Tranmere keeper Owain Fon Williams.
The Bees midfielder could have been in hot water had the incident been spotted by the officials.
Brentford (4-4-2): Moore; Logan (Hodson 46), Dean, Craig, Bidwell; Forshaw, Douglas, Diagouraga (Hayes 76), Forrester (Saunders 76); Trotta, Donaldson.
Subs not used: Lee, Barron, Reeves, Kiernan.
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